Quality of life


Patients seek QoL improvement as the primary treatment goal1

93% of patients who underwent TAVI said improved QoL was their primary treatment goal. Patients favoured the ability to enjoy their regular activities and spend time with loved ones over goals relating to heart failure symptomatology: *

Improvements in quality of life with TAVI 1

Improvements in QoL with TAVI
Data on primary quality of life goals for 46 high-surgery risk AS patients who chose TAVI over medical treatment or palliative care. The expanded pie chart only represents the 93% who expressed a QoL goal as their primary goal.

TAVI offers patients a rapid return to daily activities2

A return to daily activities is the most frequently reported goal of treatment followed by maintaining or improving independence.1 TAVI demonstrated a greater improvement of patient-defined goals at 30 days compared with surgery:2‡

Change in percentage of patients without symptoms or activity limitations at 30 days2

Quality of Life patients no symptoms
The PARTNER II Trial intermediate-risk cohort unadjusted rates, as-treated population (n=1,818). Showing representative questions of daily life activities from EuroQol-5D (EQ-5D) and short form KCCQ-12. The graph represents select categories, other daily life activities from EQ-5D and KCCQ-12. Activities captured by these quality of life measures include: hobbies or recreational activities, visiting family or friends out of their home, hurrying or jogging (as if to catch a bus) and the frequency of: shortness of breath, sleeping sitting up, and swelling in feet, ankles or legs upon waking.  Patients reporting “limited for other reasons or did not do the activity” were not included in the analysis.

TAVI demonstrates early and sustained QoL benefits in all risk groups 3, 6

Data from the PARTNER 3, II S3i, 1A and 1B Trials show that patients receiving TAVI enjoyed a better health status post-procedure compared to control group (sAVR or standard treatment), as measured using the Kansas City Cardiomyopathy Questionnaire (KCCQ).

Clinical implications

What could a TAVI referral mean for your ssAS patients?

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  • 1Coylewright M. et al. Health Expect. 2016;19(5):1036-1043.
  • 2Edwards data on file.
  • 3Baron SJ, et al. J Am Coll Cardiol. 2019;74(23):2833–2842.
  • 4Baron SJ, et al. JACC: Cardiovascular Interventions. 2018;11(12):1188-1198.
  • 5 Reynolds MR, et al. J Am Coll Cardiol 2012;60:548–558.
  • 6Reynolds MR, et al. Circulation. 2011;124:1964-1972.

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