Today, 80 is the new 701

And patients in their 80s deserve a treatment that can help keep them moving forward

When patients are faced with a treatment decision, they consider more than the data. Transcatheter aortic valve implantation (TAVI) addresses the key concerns of patients treatment decisions, including: survival, reducing the fear of heart failure, improving their quality of life, and retaining their independence.2

Patients today have a life expectancy that's nearly a decade longer compared to 40 years ago4

Patients in their 8os are less likely to be treated3

Treatment delays can have serious consequences

Nearly 40% of patients will have an unplanned hospitalization
during a waiting period of 4 months8

11.6% mortality rate at 6 months
for those waiting for AVR†9

*As compared to surgical aortic valve replacement (SAVR).
AVR = aortic valve replacement.

Timely referral is crucial

Transcatheter aortic valve implantation (TAVI) patients in their 70s and 80s showed comparable quality-of-life (QoL) improvements and clinical benefits1

Prior to treatment, QoL was self-reported by patients as poor. Post-treatment, patients in their 80s self-reported similar QoL improvement to patients in their 70s. After TAVI, patients in their 80s reported comparable QoL improvements to those patients in their 70s.

Offer your patients in their 80s a chance for more:1

Transcatheter aortic valve implantation (TAVI) patients in their 70s and 80s showed comparable quality-of-life (QoL) improvements and clinical benefits1

70 and 80 year old patients report similar KCCQ scores before AVR1

Baseline KCCQ

Comparable improvement and outcomes in KCCQ scores at 1 year include1

Post-TAVI QoL increase at 1-year

KCCQ = Kansas City Cardiomyopathy Questionnaire

NYHA class at 1 year7

NYHA class at 1 year

Patients in their 80s benefit from TAVI as much as patients in their 70s:

Clinical benefits include freedom from:1

Looking at the baseline characteristics of these two patient groups, severe AS patients in their 70s and 80s present with similar clinical characteristics:

Between both TAVI patient age groups, baseline characteristics are similar:1

ESC/EACTS VHD guidelines recommend TAVI for severe AS patients aged 75+10

Timely referral is crucial - guide your 80-year-old SAS patients to a heart team evaluation.

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Our monthly updates provide you the latest developments in TAVI and aortic stenosis.Read more

References:

1 Data on file. Edwards Lifesciences, 2022.
2 Col NF, Otero D, Lindman BR, Horne A, Levack MM, Ngo L, et al. (2022) What matters most to patients with severe aortic stenosis when choosing treatment? Framing the conversation for shared decision making. PLoS ONE 17(8):e0270209. https://doi.org/10.1371/journal.pone.0270209.
3 Eugène M, et al. Contemporary Management of Severe Symptomatic Aortic Stenosis. J Am Coll Cardiol. 2021 Nov 30;78(22):2131-2143.
4 Eurostat. Life expectancy at birth 2021. Accessed August 8, 2023.https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Table01_Life_expectancy_at_birth_2021.png.
5 OnS.gov. Office for National Statistics. https://www.ons.gov.uk/.
6 Strange GA, Stewart S, Curzen N, et al. Uncovering the treatable burden of severe aortic stenosis in the UK. Open Heart 2022;9:e001783. doi:10.1136/openhrt-2021-001783.
7 Data on file, Edwards Lifesciences.
8 Elbaz-Greener G, Yarranton B, Qui F, et al. Association between wait time for transcatheter aortic valve replacement and early postprocedural outcomes. J Am Heart Assoc. 2019;8(1):e010407.
9 Malaisrie SC, McDonald E, Kruse J, et al. Mortality while waiting for aortic valve replacement. Ann Thorac Surg. 2014;98(5):1564–1570.
10 Vahcinicin A, et. al. ESC/EACTS Scie11tific Document Group. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Hear J. 2022 Feb 12;43(7):561-632. doi: 10.1093/eurheartj/ehab395. Erratum in: Eur Heart J. 2022 Feb 18;: PMID: 34453165.

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